OSI has an established track record of innovation and meeting the highest standards of quality and professionalism among physicians, their patients, and eye banks.

We are proud of our contributions to better patient outcomes. Today we continue to work closely with surgeons to develop new tools and processes to help them perform their work more effectively and efficiently. OSI offers services in the following areas:

Penetrating Keratoplasty Services

OSI works with eye banks to obtain high quality tissue for penetrating keratoplasty. For ophthalmologists requesting that OSI perform this service, we will acquire information about transplant needs and coordinate the placement of tissue from source eye banks. We communicate with surgeons to determine in advance their tissue needs for scheduled surgeries and respond to emergent requests by providing 24-hour coordination services. This includes working with the physician’s preferred eye bank. The OSI team is well versed in penetrating and lamellar keratoplasty procedures and techniques and the tissue requirements needed to perform them. Donor tissue is obtained from eye banks accredited by the Eye Bank Association of America and registered with the U.S. Food and Drug Administration. As a matter of policy, OSI first tries to work with the physician’s preferred eye bank to obtain tissue, or as an alternate, the nearest eye bank servicing physicians in that community.

Endothelial Keratoplasty

Ocular Systems excels in the preparation of donor corneal tissue for endothelial keratoplasty (EK). Endothelial keratoplasty has been adopted worldwide as an alternative to penetrating keratoplasty in the treatment of corneal endothelial disorders.

EK helps restore vision to patients whose endothelial function is compromised from disease or age. Endothelial keratoplasty is the preferred way to restore vision when the inner cell layer of the cornea stops working properly. EK selectively replaces only the diseased layer of the cornea, leaving healthy areas intact.

Descemet’s Stripping Endothelial Keratoplasty (DSEK)

The most common type of EK procedure is known as DSEK. In this procedure the surgeon strips out the patients diseased or non-functioning cells and stroma and transplants the back 20-30% of a donor cornea into the patient’s eye.

OSI was the first company to establish the laboratory procedures and prepare DSEK corneal tissue outside of the operating room. Since then, OSI has delivered more prepared corneal tissue for DSEK than any other organization.

Descemet’s Membrane Endothelial Keratoplasty (DMEK)

Surgeons are pioneering a newer form of EK, known as DMEK. This procedure uses extremely thin donor tissue replacing only the endothelial cell layer and Descemet’s membrane. DMEK allows patients to achieve higher visual acuity. The experienced staff at OSI have perfected the technique for isolating the Descemet’s membrane for transplantation, enabling us to provide surgeons with tissue for the innovative DMEK procedure.

Corneal Tissue Reimbursement Consulting

Ocular Systems is pleased to provide its customers with reimbursement consulting to help guide you in billing corneal tissue to your local Medicare carrier and other commercial insurance carriers. Reimbursement for the acquisition of tissue used during keratoplasty procedures is a major concern for providers, patients, the physician community and medical technology innovators.

NMD Healthcare Logo

OSI customers receive reimbursement consultation services free of charge. This service is provided by Ocular Systems in collaboration NMD HealthCare Consulting, and is designed to ensure that proper, timely reimbursement is received.

NMD is fully prepared to receive and respond to all of OSI customers’ coding, coverage and reimbursement inquiries. Click here to download a brochure to learn more about the Outpatient Prospective Payment System (OPPS) and here to download the Ambulatory Surgical Center Fee Schedule.

OSI customers may access reimbursement information by contacting NMD Healthcare directly by phone at: NMD offices (609) 584-8470. You may also contact NMD by email at:support@nmdhealthcare.com.


OSI does not screen, procure, evaluate or test penetrating keratoplasty tissue. Its function is to maintain and share information about tissue demand and supply in order to provide surgeons the opportunity to maximize patient care and visual outcomes. Though based in North Carolina, OSI works with eye banks and surgeons both in the United States and internationally.

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